end of the road
end of the road or end of the line {n. phr.}
The final result or end (as of a way of action or behavior); the condition that comes when you can do no more.
He had left a trail of forgery and dishonesty across seven states; he had got out of each trouble with a new trick. Now the police had caught up with him, and it was the end of the road.
"When I get to the end of the line," Jones thought, "I'd like my children to like and respect me still."
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Source: A Dictionary of American Idioms