screw up
screw up {v. phr.}, {slang}, {semi-vulgar}, {best avoided}
1. To make a mess of, to make an error which causes confusion.
The treasurer screwed up the accounts of the Society so badly that he had to be fired.
2. To cause someone to be neurotic or maladjusted.
Her divorce screwed her up so badly that she had to go to a shrink.
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Source: A Dictionary of American Idioms